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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BROX
All Species:
37.27
Human Site:
S146
Identified Species:
74.55
UniProt:
Q5VW32
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VW32
NP_653296.2
411
46476
S146
E
A
K
E
V
H
R
S
L
K
I
A
A
G
I
Chimpanzee
Pan troglodytes
XP_001173118
411
46488
S146
E
A
K
E
V
H
R
S
L
K
I
A
A
G
I
Rhesus Macaque
Macaca mulatta
XP_001099998
411
46403
S146
E
A
K
E
V
H
R
S
L
K
I
A
A
G
I
Dog
Lupus familis
XP_536151
461
51635
S196
E
A
K
E
V
H
R
S
L
K
I
A
A
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2Q7
411
46183
S146
E
A
K
E
V
H
R
S
L
K
I
A
A
G
I
Rat
Rattus norvegicus
Q4V8K5
411
46173
S146
E
A
K
E
V
H
R
S
L
K
I
A
A
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512145
469
53140
S204
E
A
K
E
V
H
R
S
L
K
T
A
A
G
I
Chicken
Gallus gallus
XP_419397
411
46534
S146
E
A
K
D
V
H
R
S
L
K
I
A
A
G
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A3KQV2
411
46106
S146
E
A
K
D
V
H
K
S
L
K
I
A
A
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120754
420
47151
M155
E
A
K
D
V
H
T
M
L
R
R
A
A
G
I
Nematode Worm
Caenorhab. elegans
Q22885
427
48281
C156
D
A
K
E
C
L
Q
C
L
R
Q
A
G
G
M
Sea Urchin
Strong. purpuratus
XP_784283
330
36694
S76
E
V
E
S
M
E
V
S
S
G
T
G
D
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.2
84.8
N.A.
91.7
92.4
N.A.
78.4
86.3
N.A.
74.2
N.A.
N.A.
45
39.5
34.7
Protein Similarity:
100
99.7
99.5
87.1
N.A.
96.8
96.8
N.A.
82.7
92.9
N.A.
86.3
N.A.
N.A.
60
60.8
50.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
86.6
N.A.
N.A.
66.6
40
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
N.A.
100
N.A.
N.A.
80
66.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
92
0
0
0
0
0
0
0
0
0
92
84
0
0
% A
% Cys:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
25
0
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
92
0
9
67
0
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
9
0
9
9
92
0
% G
% His:
0
0
0
0
0
84
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
67
0
0
0
84
% I
% Lys:
0
0
92
0
0
0
9
0
0
75
0
0
0
0
9
% K
% Leu:
0
0
0
0
0
9
0
0
92
0
0
0
0
0
0
% L
% Met:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
67
0
0
17
9
0
0
0
0
% R
% Ser:
0
0
0
9
0
0
0
84
9
0
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
17
0
0
0
0
% T
% Val:
0
9
0
0
84
0
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _